Syntheses of 9-deazatheophyllines and 6-deoxy-9-deazatheophyllines.

Asymmetric syntheses of 1-deoxy-6,8a-di-epi-castanospermine and 1-deoxy-6-epi-castanospermine.

Asymmetric syntheses of both 1-deoxy-6,8a-di-epi-castanospermine and 1-deoxy-6-epi-castanospermine, polyhydroxylated indolizidine alkaloids that act as selective glycosidase inhibitors, have been accomplished in seven steps. The key feature of our unique syntheses includes the stereoselective introduction of the C-3 and C-4 hydroxyl groups utilizing the aza-Claisen rearrangement-induced ring ex...

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Resolving community noise problems demands not just accurate data about noise impacts but also requires an effective means of communicating this information to decision makers. The Interactive Sound Information System (ISIS) is a “new media” package designed to explain and de-mystify the complex metrics used to describe noise impacts. Central to the ISIS package is the idea that “real” noise ex...

Persian-translation Vol.9, No.6

Holiday 6/9.qxd

Breast cancer (BrCa) is one of the most frequently diagnosed cancers and the second leading cause of cancerrelated deaths in North American women. Most deaths are caused by metastasis, and BrCa is characterized by a distinct metastatic pattern involving lymph nodes, bone marrow, lung, liver and brain. Migration of metastatic cells share many similarities with leukocyte trafficking, which are re...

persian-translation vol.9, no.6

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